A high-specificity immunoassay for the therapeutic drug monitoring of cyclophosphamide

A high throughput immunoassay for the therapeutic drug monitoring of tegafur.

Cancer is a group of diseases in which abnormal cells grow and divide without control, with the potential to invade other parts of the body. Chemotherapy is a type of treatment that uses chemical agents to treat cancer. These drugs are toxic and produce undesirable adverse drug reactions due to their narrow therapeutic window and highly variable pharmacokinetics, thus, they need to be monitored...

A Review on Therapeutic Drug Monitoring of Immunosuppressant Drugs

Immunosuppressants require therapeutic drug monitoring because of their narrow therapeutic index and significant inter-individual variability in blood concentrations. This variability can be because of factors like drug-nutrient interactions, drug-disease interactions, renal-insufficiency, inflammation and infection, gender, age, polymorphism and liver mass. Drug monitoring is widely practiced ...

Analytical and clinical evaluation of a new immunoassay for therapeutic drug monitoring of infliximab and adalimumab.

In the last decade, biological agents have revolutionised rheumatology. Tumour necrosis factorα (TNF α ) neutralising antibody constructs as infl iximab and adalimumab are widely used as treatment for rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis and psoriasis. Infl iximab is a chimeric (mouse-human) monoclonal antibody against TNF α . It has been shown to induce the formati...

monitoring cyclosporine absorption: a step beyond therapeutic drug monitoring

therapeutic drug monitoring

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